NateTheHate doesn't expect any major announcement from Nintendo at TGA, Switch 2 will definitely not be at the event
Source: https://www.youtube.com/watch?v=LcUKzFDxk0s
It's a prediction podcast for the event, but the Switch 2 part was spoken with much certainty.
Personally they expect Nintendo to have an advertisement reel for the holiday season and maybe another port/remaster announcement.