What to expect? 6 rx for HBP/edema/water retention and still HBP.

My husband, 58 yrs old, 6’2”, 350# Non smoker, no exercise, drinks 3-8 bourbon cocktails most nights (I am estimating here bc just like his eating his drinks are way out portion control). Drinks 24oz of water (that I know of). Eating habits are mostly portions way beyond than what he should have (he eats a whole frozen pizza in one sitting) and hides fast food. I know the obvious that he needs to reign in the drinking and eating, needs to exercise (move in general) and drink more water at bare minimum. Myself and the kids have brought these things to his attention, but fails to do anything. His dad died in his early 60s bc of cancer and a stroke. His mom died her early 60s (maybe 62) of heart failure I believe. She was over 400# at death.